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TG Therapeutics Licenses Ligand’s IRAK4 Program

Preclinical candidate has potential to treat cancer and autoimmune disorders

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By: Kristin Brooks

Managing Editor, Contract Pharma

TG Therapeutics entered a licensing agreement with Ligand Pharmaceuticals for exclusive global rights to develop and commercialize Ligand’s IRAK4 inhibitor research program currently in preclinical development.   IRAK4 is a signaling kinase associated with mutations of MYD88, which can be found in most patients with Waldenstrom’s Macroglobulinemia, a rare B-cell cancer, and certain patients with Non-Hodgkin’s Lymphoma and chronic lymphocytic leukemia. Additionally, IRAK4 is a k...

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